Quercetin vs Epigallocatechin gallate: what is the difference?
Quercetin is a flavonol found in onions and apples, while epigallocatechin gallate is a larger flavan-3-ol from green tea with an extra gallate ester.
Sources and notes
- The sentence under the titlefrom sourceMoleculeFinder comparison notesThe pair's answer line.
- The two drawingscomputedMoleculeFinder rule (RDKit MCS)Drawn the same way round on the skeleton they share. Aligned; 13 atoms differ, too many to mark as one group.
Side by side
| Quercetin | Epigallocatechin gallate | |
|---|---|---|
| Molecular weightCalculated PubChem | 302.23 g/molC15H10O7 | 458.4 g/molC22H18O11 |
| Hydrogen-bond donorsCalculated PubChem | 5 | 8 |
| Where each turns upEditorial MoleculeFinder food and product lists |
|
|
| FamilyEditorial MoleculeFinder curated | Flavonoids | Flavonoids |
| Everyday groupEditorial MoleculeFinder curated | Plant | Plant |
| Chemical groupsCalculated Found by rule (RDKit) | Aromatics, Phenols | Aromatics, Esters, Phenols, Ethers |
| Hazard labelReported ECHA via PubChem | Danger | Warning |
| The supplier-filed hazard label's signal word, not a statement about ordinary use. | ||
| Oral LD50Measured HSDB via PubChem | 161 mg/kgpure quercetin, rat, oral | Not recorded |
| A single acute animal measure. It ranks nothing about human safety. | ||
Sources and notes
- Molecular weightcomputedPubChemComputed from the structure; the formula is under each weight.
- Hydrogen-bond donorscomputedPubChemThe hydrogens on nitrogen or oxygen that each molecule can lend to a hydrogen bond, counted from its structure.
- Where each turns upfrom sourceMoleculeFinder food and product listsEach amount is an editorial figure from our lists, not a measurement of any one product. Each mark is set by hand on the list, never inferred.
- Familyfrom sourceMoleculeFinder curated
- Everyday groupfrom sourceMoleculeFinder curated
- Chemical groupscomputedFound by rule (RDKit)Each group is found in the structure by a chemical pattern.
- Hazard labelfrom sourceECHA via PubChem
- Oral LD50from sourceHSDB via PubChem
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Identifiersfrom sourcePubChemPubChem CID 5280343 (Quercetin) and 65064 (Epigallocatechin gallate).
In more detail
Both are plant polyphenols with antioxidant reputations and they come from different chemical families. Quercetin is a flavonol with a flat, conjugated three-ring core and five hydroxyl groups, widespread in onions, apples, capers and tea. Epigallocatechin gallate is a flavan-3-ol from green tea specifically, much larger at 458.4 against 302.2, and its extra gallate ester adds a fourth ring carrying three more hydroxyl groups. EGCG is also the more unstable of the two, oxidising readily in warm water and in the gut, which complicates dose comparisons between studies. Both bind proteins and metal ions readily, which is part of why both interfere with the absorption of iron from a meal.
Sources and notes
- The paragraphfrom sourceMoleculeFinder comparison notes
Questions
- What is the difference between Quercetin and Epigallocatechin gallate?
- Quercetin is a flavonol found in onions and apples, while epigallocatechin gallate is a larger flavan-3-ol from green tea with an extra gallate ester.
- Is Quercetin bigger than Epigallocatechin gallate?
- Epigallocatechin gallate is the heavier molecule, 458.4 g/mol against 302.23 g/mol for Quercetin. Quercetin is C15H10O7 and Epigallocatechin gallate is C22H18O11.
Sources and notes
- The answersfrom sourceMoleculeFinderThe first is the pair's answer line; the others are read off the table above.