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SHEET /m/zidovudine · PubChem CID 35370 · CAS 30516-87-1 · REV 2026.07

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Zidovudine

from source

C10H13N5O4 · 267.24 g/mol

AZT · Azidothymidine · ZDV · Compound S

What is Zidovudine?

Known as AZT, the first medicine approved to treat HIV, in 1987. It mimics thymidine, one of DNA's building blocks, and jams the virus's copying enzyme. from source

Chemical familyAlcoholsEthers
LeaderboardsBiggest

Fig. 1 · 2D structure RDKit

SMILESCC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Toxicity & hazards

Toxicity · LD50

750 mg/kg · low toxicity · LD50 rat iv from source

1 more reported value
  • 3,000 mg/kgLD50 · iv · mouse
DangerHealth hazardH341, H350, H351, H361, H362, H370, H372from source

Sources & methodology

PubChem CID
35370
Wikidata
Q198504
Structure
PubChem → RDKit
LD50
PubChem
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