moleculefinder

Vortioxetine

C18H22N2S298.4 g/mol Calculated

Also called Trintellix and Brintellix.

An antidepressant sold as Trintellix, used for major depressive disorder. Vortioxetine (C18H22N2S, 298 g/mol) is an antidepressant dispensed on prescription.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Vortioxetine on the product labels we hold.

Medicines

TrintellixAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A nitrogen carrying one or two hydrogens. Its spare pair of electrons can pick up a hydrogen ion, so an amine is a base.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Properties and sources

Calculated by PubChem

Molecular formula
C18H22N2S
Molecular weight
298.4 g/mol
XLogP3octanol/water, log units
4.2
Polar surface areatopological
40.6 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Complexity
316

Reported Hazard label (GHS), ECHA via PubChem

Warning Irritant pictogram (GHS07), Health hazard pictogram (GHS08) and Environmental pictogram (GHS09); hazard statements H302, H361, H371, H373, H400, H410

Reported Licence

The US Food and Drug Administration licenses Vortioxetine for human use (NDA 204447, authorized September 30, 2013). Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Antidepressants
Chemical groups
Amines, Aromatics
Elements
Nitrogen, Sulfur
Hazard classes
Irritant, Health hazard, Environmental hazard, GHS Warning
SMILESCC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C

PubChem CID 9966051 · Wikidata Q3563148 · InChIKey YQNWZWMKLDQSAC-UHFFFAOYSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Vortioxetine?
An antidepressant sold as Trintellix, used for major depressive disorder. Vortioxetine (C18H22N2S, 298 g/mol) is an antidepressant dispensed on prescription.
How toxic is Vortioxetine?
Its GHS hazard label carries the signal word Warning and the hazard pictograms Irritant, Health hazard and Environmental. from source
What kind of molecule is Vortioxetine?
Vortioxetine has the formula C18H22N2S and a molecular weight of 298.4 g/mol. MoleculeFinder files it under antidepressants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
What else is Vortioxetine called?
Vortioxetine is also called Brintellix and Trintellix. from source
Who licenses Vortioxetine as a medicine?
The US Food and Drug Administration licenses Vortioxetine for human use (NDA 204447, authorized September 30, 2013). from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09