SHEET /m/triclosan · PubChem CID 5564 · CAS 3380-34-5 · REV 2026.07
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Triclosan from source
C12H7Cl3O2 · 289.5 g/mol
Cloxifenolum · 2,4,4'-Trichloro-2'-hydroxydiphenyl ether · Triclosanum · Irgasan DP300
antimicrobial agent
CategoryEveryday chemistry
Chemical familyAromatics
Fig. 1 · 2D structure RDKit
C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl
Where you'll find it
Not yet mapped to everyday foods or products.
The dose makes the poison inferred
A reported rat oral LD50 for Triclosan is 3,700 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
259.0 g
a median lethal dose scaled to 154 lb (259,000 mg)
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
3,700 mg/kg · very low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
3 more reported values
- 19 mg/kgLD50 · iv · rat
- 3,900 mg/kgLD50 · other · rat
- 9,300 mg/kgLD50 · dermal · rat
DangerToxicIrritantEnvironmentalH315, H319, H331, H335, H400, H410from source