moleculefinder

Trazodone

C19H22ClN5O371.9 g/mol Calculated

Also called Beneficat, Desirel, Molipaxin and Trazalon.

An antidepressant, sold as Desyrel, prescribed for depression and very often for insomnia because it is sedating.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourcePubChem / Wikidata
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Trazodone on the product labels we hold.

Medicines

RaldesyAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A nitrogen bonded to three carbons, with no hydrogen of its own. Its spare pair of electrons can still pick up a hydrogen ion, so a tertiary amine is a base.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Properties and sources

Calculated by PubChem

Molecular formula
C19H22ClN5O
Molecular weight
371.9 g/mol
XLogP3octanol/water, log units
2.8
Polar surface areatopological
42.4 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Complexity
611

Measured LD50, HSDB via PubChem

690 mg/kg pure trazodone, rat, oral

An LD50 is an animal study measurement, not a dose for a person.

Reported Hazard label (GHS), ECHA, HSDB via PubChem

Warning Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H302, H351

Reported Licence

The US Food and Drug Administration licenses Trazodone for human use (NDA 218637, authorized November 26, 2024), as Raldesy. Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Antidepressants
Chemical groups
Aromatics, Halogenated
Elements
Chlorine, Nitrogen
Hazard classes
Irritant, Health hazard, GHS Warning
SMILESC1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl

PubChem CID 5533 · Wikidata Q411457 · InChIKey PHLBKPHSAVXXEF-UHFFFAOYSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Trazodone?
An antidepressant, sold as Desyrel, prescribed for depression and very often for insomnia because it is sedating.
How toxic is Trazodone?
The reported LD50 of Trazodone is 690 mg/kg (rat, oral). An LD50 is an animal study measurement, not a dose for a person. Its GHS hazard label carries the signal word Warning and the hazard pictograms Irritant and Health hazard. from sourcefrom source
What kind of molecule is Trazodone?
Trazodone has the formula C19H22ClN5O and a molecular weight of 371.9 g/mol. MoleculeFinder files it under antidepressants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
Who licenses Trazodone as a medicine?
The US Food and Drug Administration licenses Trazodone for human use (NDA 218637, authorized November 26, 2024), as Raldesy. from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • LD50from sourceHSDB via PubChemOther values the sources report: mouse, oral, 610 mg/kg; rat, intravenous, 91 mg/kg; mouse, intravenous, 91 mg/kg; rat, another route, 178 mg/kg. The page shows the one LD50 the site uses everywhere.
  • Hazard labelfrom sourceECHA, HSDB via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09