moleculefinder

Topiramate

C12H21NO8S339.36 g/mol Calculated

Also called Topamax and TPM.

An anticonvulsant sold as Topamax, used for epilepsy and for migraine prevention. Topiramate (C12H21NO8S, 339 g/mol) is an anticonvulsant dispensed on prescription.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Topiramate on the product labels we hold.

Medicines

TopamaxAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

One carbon bonded to two oxygens, each joined in turn to another carbon. It is the kind of link that joins sugars together: it stands up to bases, and acid splits it.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Properties and sources

Calculated by PubChem

Molecular formula
C12H21NO8S
Molecular weight
339.36 g/mol
XLogP3octanol/water, log units
−0.8
Polar surface areatopological
124 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
3
Complexity
556

Reported Hazard label (GHS), ECHA via PubChem

Warning Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H315, H319, H335, H361

Reported Licence

The US Food and Drug Administration licenses Topiramate for human use (NDA 020505, authorized December 24, 1996). Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Anticonvulsants
Chemical groups
Amines, Ethers
Elements
Nitrogen, Sulfur
Hazard classes
Irritant, Health hazard, GHS Warning
SMILESCC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C

PubChem CID 5284627 · Wikidata Q221174 · InChIKey KJADKKWYZYXHBB-XBWDGYHZSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Topiramate?
An anticonvulsant sold as Topamax, used for epilepsy and for migraine prevention. Topiramate (C12H21NO8S, 339 g/mol) is an anticonvulsant dispensed on prescription.
How toxic is Topiramate?
Its GHS hazard label carries the signal word Warning and the hazard pictograms Irritant and Health hazard. from source
What kind of molecule is Topiramate?
Topiramate has the formula C12H21NO8S and a molecular weight of 339.36 g/mol. MoleculeFinder files it under anticonvulsants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
What else is Topiramate called?
Topiramate is also called TPM and Topamax. from source
Who licenses Topiramate as a medicine?
The US Food and Drug Administration licenses Topiramate for human use (NDA 020505, authorized December 24, 1996). from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09