moleculefinder

Tirzepatide

C225H348N48O684813 g/mol Calculated

Also called Zepbound.

A dual GIP and GLP-1 peptide for type 2 diabetes and weight loss, sold as Mounjaro and Zepbound. A fatty chain on its 39 amino acids lets it ride on albumin in the blood for days.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit

Where you encounter it

Dispensed on prescription, not sold on a shelf. Tirzepatide on the product labels we hold.

Medicines

MounjaroAdded by the makerActive ingredient
ZepboundAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Compare a related molecule

Semaglutide acts on the GLP-1 receptor alone, while tirzepatide hits both the GIP and GLP-1 receptors, the basis for its larger reported weight loss.

Semaglutide vs Tirzepatide, side by side
Sources and notes
  • The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.

Properties and sources

Calculated by PubChem

Molecular formula
C225H348N48O68
Molecular weight
4813 g/mol
XLogP3octanol/water, log units
−6.8
Polar surface areatopological
1790 Ų
H-bond donors
58
H-bond acceptors
70
Rotatable bonds
163
Complexity
11700

Reported Hazard label (GHS), ECHA via PubChem

Warning Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H302, H312, H315, H319, H332

Reported Licence

The US Food and Drug Administration licenses Tirzepatide for human use (NDA 215866, authorized May 13, 2022), as Mounjaro. Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Diabetes medicines
Chemical groups
Alcohols, Carboxylic Acids, Amines, Aromatics, Amides, Phenols, Ethers
Elements
Nitrogen
Hazard classes
Irritant, Health hazard, GHS Warning
Size
Over 1000 g/mol
SMILESCC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC…792 characters

PubChem CID 156588324 · Wikidata Q108324770 · InChIKey AAPYRSPHYSKGIS-MCNPHUAVSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Tirzepatide?
A dual GIP and GLP-1 peptide for type 2 diabetes and weight loss, sold as Mounjaro and Zepbound. A fatty chain on its 39 amino acids lets it ride on albumin in the blood for days.
How toxic is Tirzepatide?
Its GHS hazard label carries the signal word Warning and the hazard pictograms Irritant and Health hazard. from source
What kind of molecule is Tirzepatide?
Tirzepatide has the formula C225H348N48O68 and a molecular weight of 4,813 g/mol. MoleculeFinder files it under diabetes medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
What else is Tirzepatide called?
Tirzepatide is also called Zepbound. from source
Who licenses Tirzepatide as a medicine?
The US Food and Drug Administration licenses Tirzepatide for human use (NDA 215866, authorized May 13, 2022), as Mounjaro. from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09

Keep exploring

Compared side by side with tirzepatideSemaglutideC187H291N45O59Also a diabetes medicineLiraglutideC172H265N43O51Both carry a phenol, an alcohol and a carboxylic acid group.CalcitoninC151H228N40O45S3Both carry an alcohol, a carboxylic acid and an amide group.CholecystokininC166H261N51O52S4
More related molecules
  • Glucagon Both carry a phenol, an alcohol and a carboxylic acid group.
  • Tesamorelin Both carry a phenol, an alcohol and a carboxylic acid group.
  • Ghrelin Both carry an alcohol, a carboxylic acid and an amide group.
  • Vasoactive intestinal peptide Both carry a phenol, an alcohol and a carboxylic acid group.
  • Insulin Both carry a phenol, an alcohol and a carboxylic acid group.
  • Substance P Both carry an amide and an amine group.
Sources and notes
  • Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
  • The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
  • Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.