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SHEET /m/tapentadol · PubChem CID 9838022 · CAS 175591-23-8 · REV 2026.07

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Tapentadol

from source

C14H23NO · 221.34 g/mol

What is Tapentadol?

An opioid painkiller that also acts on norepinephrine, used for moderate to severe pain. Tapentadol (C14H23NO, 221 g/mol) is an opioid dispensed on prescription. from source

Chemical familyAromaticsPhenols
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCC[C@@H](C1=CC(=CC=C1)O)[C@@H](C)CN(C)C

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
300 mg/kg · moderately toxic
Species
mouse
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

300 mg/kg · moderately toxic · LD50 mouse oral from source

1 more reported value
  • 40 mg/kgLD50 · iv · rat
WarningIrritantHealth hazardEnvironmentalH302, H361, H411from source

Keep roaming

Where Tapentadol leads

Sources & methodology

PubChem CID
9838022
Wikidata
Q414463
Structure
PubChem → RDKit
LD50
PubChem
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