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SHEET /m/sulfamethoxazole · PubChem CID 5329 · CAS 723-46-6 · REV 2026.07

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Sulfamethoxazole

from source

C10H11N3O3S · 253.28 g/mol

Urobak · SMZ · Sinomin · Gantanol

What is Sulfamethoxazole?

A sulfonamide antibiotic usually paired with trimethoprim as co-trimoxazole, sold as Bactrim and Septra. It stops bacteria from making folate. from source

Chemical familyAminesAromatics
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
6,370 mg/kg · very low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

6,370 mg/kg · very low toxicity · LD50 rat oral from source

4 more reported values
  • 2,650 mg/kgLD50 · oral · mouse
  • 3,662 mg/kgLD50 · oral · mouse
  • 2,300 mg/kgLD50 · other · mouse
  • 2,690 mg/kgLD50 · other · rat
DangerIrritantHealth hazardEnvironmentalH315, H317, H319, H335, H341, H350, H400, H410from source

Sources & methodology

PubChem CID
5329
Wikidata
Q415843
Structure
PubChem → RDKit
LD50
PubChem
Data refreshed

How MoleculeFinder sources and labels its data