SHEET /m/sulfamethoxazole · PubChem CID 5329 · CAS 723-46-6 · REV 2026.07
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Sulfamethoxazole
from sourceC10H11N3O3S · 253.28 g/mol
Urobak · SMZ · Sinomin · Gantanol
What is Sulfamethoxazole?
A sulfonamide antibiotic usually paired with trimethoprim as co-trimoxazole, sold as Bactrim and Septra. It stops bacteria from making folate. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)NWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 6,370 mg/kg · very low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
6,370 mg/kg · very low toxicity · LD50 rat oral from source
4 more reported values
- 2,650 mg/kgLD50 · oral · mouse
- 3,662 mg/kgLD50 · oral · mouse
- 2,300 mg/kgLD50 · other · mouse
- 2,690 mg/kgLD50 · other · rat
DangerIrritantHealth hazardEnvironmentalH315, H317, H319, H335, H341, H350, H400, H410from source