moleculefinder

Rosuvastatin

C22H28FN3O6S481.5 g/mol Calculated

Also called Creston and X-Plended.

The cholesterol-lowering statin sold as Crestor. In enzyme tests it grips its target, HMG-CoA reductase, more tightly than the other statins do.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourcePubChem / Wikidata
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Rosuvastatin on the product labels we hold.

Medicines

CrestorAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A carbon carrying both a C=O and an O-H, written COOH. In water it gives up that hydrogen, which is what makes the molecule an acid.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Compare a related molecule

Atorvastatin

Rosuvastatin

Both are statins, but rosuvastatin is more potent per unit weight and is largely not cleared by CYP3A4, so it has fewer interactions than atorvastatin.

Atorvastatin vs Rosuvastatin, side by side
Sources and notes
  • The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
  • The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.

Properties and sources

Calculated by PubChem

Molecular formula
C22H28FN3O6S
Molecular weight
481.5 g/mol
XLogP3octanol/water, log units
1.6
Polar surface areatopological
149 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
10
Complexity
767

Reported Hazard label (GHS), ECHA via PubChem

Danger Health hazard pictogram (GHS08) and Environmental pictogram (GHS09); hazard statements H351, H360, H411, H412

Reported Licence

The US Food and Drug Administration licenses Rosuvastatin for human use (NDA 021366, authorized August 12, 2003), as Crestor. Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Cholesterol medicines
Chemical groups
Alcohols, Carboxylic Acids, Aromatics, Halogenated
Elements
Fluorine, Nitrogen, Sulfur
Hazard classes
Health hazard, Environmental hazard, GHS Danger
SMILESCC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

PubChem CID 446157 · Wikidata Q415159 · InChIKey BPRHUIZQVSMCRT-VEUZHWNKSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Rosuvastatin?
The cholesterol-lowering statin sold as Crestor. In enzyme tests it grips its target, HMG-CoA reductase, more tightly than the other statins do.
How toxic is Rosuvastatin?
Its GHS hazard label carries the signal word Danger and the hazard pictograms Health hazard and Environmental. from source
What kind of molecule is Rosuvastatin?
Rosuvastatin has the formula C22H28FN3O6S and a molecular weight of 481.5 g/mol. MoleculeFinder files it under cholesterol medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
Who licenses Rosuvastatin as a medicine?
The US Food and Drug Administration licenses Rosuvastatin for human use (NDA 021366, authorized August 12, 2003), as Crestor. from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09

Keep exploring

Compared side by side with rosuvastatinAtorvastatinC33H35FN2O5
Sources and notes
  • Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
  • The drawingscomputedPubChem structures, drawn by RDKit