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SHEET /m/resiniferatoxin · PubChem CID 5702546 · CAS 57444-62-9 · REV 2026.07

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Resiniferatoxin

from source

C37H40O9 · 628.7 g/mol

RTX · Lopain · Neuroclastin · RTX diterpene

What is Resiniferatoxin?

The most powerfully pungent compound known, from a Moroccan cactus-like spurge. It is roughly a thousand times hotter than pure capsaicin. from source

CategoryPlant
LeaderboardsBiggestSpiciest

Fig. 1 · 2D structure RDKit

SMILESC[C@@H]1C[C@]2([C@H]3[C@H]4[C@]1([C@@H]5C=C(C(=O…125 characters

How hot is it? computed

16,000,000,000 SHU
Resiniferatoxin is 3,200,000× hotter than

Signature properties

Scoville heat16,000,000,000 SHUcomputed

Toxicity & hazards

DangerCorrosiveToxicH301, H314from source

Sources & methodology

PubChem CID
5702546
Wikidata
Q3277888
Structure
PubChem → RDKit
Data refreshed

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