Pregabalin
Also called Lyrica and Vronogabic.
An anticonvulsant sold as Lyrica, used for nerve pain, fibromyalgia and some seizure types. Like gabapentin it is built on the GABA skeleton.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourcePubChem / Wikidata
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Pregabalin on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A carbon carrying both a C=O and an O-H, written COOH. In water it gives up that hydrogen, which is what makes the molecule an acid.
From: standard chemistry.
A nitrogen carrying one or two hydrogens. Its spare pair of electrons can pick up a hydrogen ion, so an amine is a base.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Compare a related molecule
Gabapentin
Pregabalin
Gabapentin and pregabalin bind the same calcium channel subunit, but pregabalin is absorbed predictably and gabapentin less so as the amount rises.
Gabapentin vs Pregabalin, side by sideSources and notes
- The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
- The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.
Properties and sources
Calculated by PubChem
- Molecular formula
- C8H17NO2
- Molecular weight
- 159.23 g/mol
- XLogP3octanol/water, log units
- −1.6
- Polar surface areatopological
- 63.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Rotatable bonds
- 5
- Complexity
- 123
Reported Hazard label (GHS), ECHA via PubChem
Danger Corrosive pictogram (GHS05) and Health hazard pictogram (GHS08); hazard statements H318, H361, H373
Reported Licence
The US Food and Drug Administration licenses Pregabalin for human use (NDA 021446, authorized December 30, 2004). Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Anticonvulsants
- Chemical groups
- Carboxylic Acids, Amines
- Elements
- Nitrogen
- Hazard classes
- Corrosive, Health hazard, GHS Danger
CC(C)C[C@@H](CC(=O)O)CNPubChem CID 5486971 · Wikidata Q412174 · InChIKey AYXYPKUFHZROOJ-ZETCQYMHSA-N · Data refreshed
Questions
- What is Pregabalin?
- An anticonvulsant sold as Lyrica, used for nerve pain, fibromyalgia and some seizure types. Like gabapentin it is built on the GABA skeleton.
- How toxic is Pregabalin?
- Its GHS hazard label carries the signal word Danger and the hazard pictograms Corrosive and Health hazard. from source
- What kind of molecule is Pregabalin?
- Pregabalin has the formula C8H17NO2 and a molecular weight of 159.23 g/mol. MoleculeFinder files it under anticonvulsants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- Who licenses Pregabalin as a medicine?
- The US Food and Drug Administration licenses Pregabalin for human use (NDA 021446, authorized December 30, 2004). from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
More related molecules
- Baclofen Both carry a carboxylic acid and an amine group.
- Aspartic acid Both carry a carboxylic acid and an amine group.
Sources and notes
- Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit