SHEET /m/oxymetazoline · PubChem CID 4636 · CAS 1491-59-4 · REV 2026.07
Oxymetazoline from source
C16H24N2O · 260.37 g/mol
Oxymethazoline · Hazol · Oximetazolinum · Oxylazine
Also sold as Afrin, Vicks Sinex, Zicam from source
a topical decongestant
Fig. 1 · 2D structure RDKit
CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C
Where you'll find it
Not yet mapped to everyday foods or products.
The dose makes the poison inferred
A reported rat oral LD50 for Oxymetazoline is 0.8 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
0.8 mg/kg · extremely toxic · LD50 rat oral from source
The dose lens above scales this to a body weight.
1 more reported value
- 1.1 mg/kgLD50 · other · rat