moleculefinder

Metoclopramide

C14H22ClN3O2299.79 g/mol Calculated

Also called Elieten, Methoxyclopramide, Reliveran and Terperan.

An anti-nausea medicine that also speeds the stomach's emptying, used for reflux and gastroparesis. Metoclopramide (C14H22ClN3O2, 300 g/mol) is an anti-nausea medicine dispensed on prescription.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourcePubChem / Wikidata
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Metoclopramide on the product labels we hold.

Medicines

ReglanAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A C=O bonded to a nitrogen, the same link that joins amino acids in a protein. It is sturdy, and its nitrogen is not a base the way an amine's is.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Properties and sources

Calculated by PubChem

Molecular formula
C14H22ClN3O2
Molecular weight
299.79 g/mol
XLogP3octanol/water, log units
2.6
Polar surface areatopological
67.6 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
7
Complexity
300

Measured LD50, HSDB via PubChem

750 mg/kg pure metoclopramide, rat, oral

An LD50 is an animal study measurement, not a dose for a person.

Reported Hazard label (GHS), ECHA via PubChem

Danger Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H302, H362, H370

Reported Licence

The US Food and Drug Administration licenses Metoclopramide for human use (NDA 017854, authorized December 30, 1980). Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Anti-nausea medicines
Chemical groups
Amines, Aromatics, Amides, Ethers, Halogenated
Elements
Chlorine, Nitrogen
Hazard classes
Irritant, Health hazard, GHS Danger
SMILESCCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl

PubChem CID 4168 · Wikidata Q421095 · InChIKey TTWJBBZEZQICBI-UHFFFAOYSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Metoclopramide?
An anti-nausea medicine that also speeds the stomach's emptying, used for reflux and gastroparesis. Metoclopramide (C14H22ClN3O2, 300 g/mol) is an anti-nausea medicine dispensed on prescription.
How toxic is Metoclopramide?
The reported LD50 of Metoclopramide is 750 mg/kg (rat, oral). An LD50 is an animal study measurement, not a dose for a person. Its GHS hazard label carries the signal word Danger and the hazard pictograms Irritant and Health hazard. from sourcefrom source
What kind of molecule is Metoclopramide?
Metoclopramide has the formula C14H22ClN3O2 and a molecular weight of 299.79 g/mol. MoleculeFinder files it under anti-nausea medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
Who licenses Metoclopramide as a medicine?
The US Food and Drug Administration licenses Metoclopramide for human use (NDA 017854, authorized December 30, 1980). from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • LD50from sourceHSDB via PubChemOther values the sources report: rat, intravenous, 50 mg/kg; rat, another route, 114 mg/kg; rat, another route, 340 mg/kg. The page shows the one LD50 the site uses everywhere.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09