Methylprednisolone
Also called Dopomedrol, Medesone, Medrate and Medrone.
A corticosteroid used for inflammation and autoimmune flares, familiar as the tapering dose pack. Methylprednisolone (C22H30O5, 374 g/mol) is a corticosteroid dispensed on prescription.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourcePubChem / Wikidata
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Methylprednisolone on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A C=O with a carbon on each side. Its oxygen accepts hydrogen bonds but has no hydrogen to give, and it resists oxidation better than an aldehyde.
From: standard chemistry.
An O-H on a carbon that is not part of an aromatic ring, the group that makes a molecule an alcohol. It both gives and accepts hydrogen bonds, which helps the molecule mix with water.
From: standard chemistry.
Rings joined where they share atoms, or a single ring standing alone. Atoms in a ring are held in place, so this part keeps its shape while chains around it can bend.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C22H30O5
- Molecular weight
- 374.5 g/mol
- XLogP3octanol/water, log units
- 1.9
- Polar surface areatopological
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Rotatable bonds
- 2
- Complexity
- 754
Measured LD50, HSDB via PubChem
3,000 mg/kg pure methylprednisolone, rat, another route
An LD50 is an animal study measurement, not a dose for a person.
Reported Hazard label (GHS), ECHA via PubChem
Danger Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H302, H312, H360, H361, H372, H373
Reported Licence
The US Food and Drug Administration licenses Methylprednisolone for human use (NDA 011153, authorized October 24, 1957), as Medrol. Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Corticosteroids
- Hazard classes
- Irritant, Health hazard, GHS Danger
C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H…87 charactersPubChem CID 6741 · Wikidata Q417222 · InChIKey VHRSUDSXCMQTMA-PJHHCJLFSA-N · Data refreshed
Questions
- What is Methylprednisolone?
- A corticosteroid used for inflammation and autoimmune flares, familiar as the tapering dose pack. Methylprednisolone (C22H30O5, 374 g/mol) is a corticosteroid dispensed on prescription.
- How toxic is Methylprednisolone?
- The reported LD50 of Methylprednisolone is 3,000 mg/kg (rat, other). An LD50 is an animal study measurement, not a dose for a person. Its GHS hazard label carries the signal word Danger and the hazard pictograms Irritant and Health hazard. from sourcefrom source
- What kind of molecule is Methylprednisolone?
- Methylprednisolone has the formula C22H30O5 and a molecular weight of 374.5 g/mol. MoleculeFinder files it under corticosteroids, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- Who licenses Methylprednisolone as a medicine?
- The US Food and Drug Administration licenses Methylprednisolone for human use (NDA 011153, authorized October 24, 1957), as Medrol. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- LD50from sourceHSDB via PubChem
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
More related molecules
- Dexamethasone Also a corticosteroid
- Betamethasone Also a corticosteroid
- Triamcinolone Also a corticosteroid
- Cortisol Both carry an alcohol and a ketone group.
Sources and notes
- The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit