Methoxyflurane
Also called Metoxiflurano.
An inhaled anaesthetic, still carried by ambulances in Australia and Europe as the green whistle for pain at the roadside.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf.
Sources and notes
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
An oxygen bridging two carbons, written C-O-C. It accepts hydrogen bonds but has no hydrogen to give, and it is slow to react.
From: standard chemistry.
Fluorine, chlorine, bromine or iodine bonded to carbon. Each pulls electrons toward itself, and each is larger than the hydrogen the carbon would otherwise carry.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C3H4Cl2F2O
- Molecular weight
- 164.96 g/mol
- XLogP3octanol/water, log units
- 2.2
- Polar surface areatopological
- 9.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Rotatable bonds
- 2
- Complexity
- 75
Reported Hazard label (GHS), ECHA via PubChem
Warning Flammable pictogram (GHS02), Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H226, H315, H319, H335, H341
Reported Licence
The Medicines and Healthcare products Regulatory Agency licenses Methoxyflurane for human use, as Penthrox. MHRA Products
Groups it belongs to
- Category
- Prescription medicine
- Family
- Anaesthetics
- Chemical groups
- Ethers, Halogenated
- Hazard classes
- Flammable, Irritant, Health hazard, GHS Warning
COC(C(Cl)Cl)(F)FPubChem CID 4116 · Wikidata Q411594 · InChIKey RFKMCNOHBTXSMU-UHFFFAOYSA-N · Data refreshed
Questions
- What is Methoxyflurane?
- An inhaled anaesthetic, still carried by ambulances in Australia and Europe as the green whistle for pain at the roadside.
- How toxic is Methoxyflurane?
- Its GHS hazard label carries the signal word Warning and the hazard pictograms Flammable, Irritant and Health hazard. from source
- What kind of molecule is Methoxyflurane?
- Methoxyflurane has the formula C3H4Cl2F2O and a molecular weight of 164.96 g/mol. MoleculeFinder files it under anaesthetics, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- What else is Methoxyflurane called?
- Methoxyflurane is also called Metoxiflurano. from source
- Who licenses Methoxyflurane as a medicine?
- The Medicines and Healthcare products Regulatory Agency licenses Methoxyflurane for human use, as Penthrox. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceMHRA ProductsRead 2026-10-21. Contains public sector information licensed under the Open Government Licence v3.0.
- Data refreshedfrom sourceMoleculeFinder2026-11-09