SHEET /m/methadone · PubChem CID 4095 · CAS 76-99-3 · REV 2026.07
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Methadone
from sourceC21H27NO · 309.4 g/mol
Adanon · Algovetin · Amidone · Diaminon
What is Methadone?
A long-acting opioid used for opioid use disorder and for chronic pain. Its long stay in the body is the point: one dose covers a day. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2Where you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 86 mg/kg · moderately toxic
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
86 mg/kg · moderately toxic · LD50 rat oral from source
3 more reported values
- 11 mg/kgLD50 · iv · rat
- 18 mg/kgLD50 · other · rat
- 30 mg/kgLD50 · other · rat
DangerToxicIrritantH300, H336, H412from source