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SHEET /m/metformin · PubChem CID 4091 · CAS 657-24-9 · REV 2026.07

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Metformin

from source

C4H11N5 · 129.16 g/mol

DMBG · dimethylbiguanide · Diaformin · Metiguanide

What is Metformin?

The first-line medicine for type 2 diabetes, descended from a compound in the goat's rue plant. It is a tiny molecule: four carbons and five nitrogens. from source

Chemical familyAmines
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCN(C)C(=N)N=C(N)N

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
1,000 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

1,000 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values
  • 180 mg/kgLD50 · iv · mouse
  • 300 mg/kgLD50 · other · rat
  • 620 mg/kgLD50 · other · mouse
WarningIrritantH302, H315, H319from source

Compare with

Sources & methodology

PubChem CID
4091
Wikidata
Q19484
Structure
PubChem → RDKit
LD50
PubChem
Data refreshed

How MoleculeFinder sources and labels its data