SHEET /m/menthol · PubChem CID 16666 · CAS 2216-51-5 · REV 2026.07
Menthol
from sourceC10H20O · 156.26 g/mol
levomentol · peppermint camphor
What is Menthol?
The cold feeling of peppermint, chewing gum, and cough drops. It does not lower the temperature, it opens the same nerve channel that real cold does. from source
Fig. 1 · 2D structure RDKit
C[C@@H]1CC[C@H]([C@@H](C1)O)C(C)CWhere you'll find it
Curated by MoleculeFinder from source
The dose makes the poison inferred
A reported rat oral LD50 for Menthol is 3,300 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
3,300 mg/kg · very low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
4 more reported values
- 3,400 mg/kgLD50 · oral · mouse
- 10,001 mg/kgLD50 · oral · rat
- 700 mg/kgLD50 · other · rat
- 6,600 mg/kgLD50 · other · mouse
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