moleculefinder

SHEET /m/loratadine · PubChem CID 3957 · CAS 79794-75-5 · REV 2026.07

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Loratadine from source

C22H23ClN2O2 · 382.9 g/mol

Claritin · Alavert · Clarityn · Clarityne

Also sold as Claritin, Alavert from source

chemical compound; medication used to treat allergies

CategoryOTC medicine
Chemical familyAromatics
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

Where you'll find it

Not yet mapped to everyday foods or products.

The dose makes the poison inferred

A reported rat oral LD50 for Loratadine is 5,000 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

350.0 g
a median lethal dose scaled to 154 lb (350,000 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Toxicity & hazards

Toxicity · LD50

5,000 mg/kg · very low toxicity · LD50 rat oral from source

The dose lens above scales this to a body weight.

1 more reported value
  • 5,000 mg/kgLD50 · oral · mouse
DangerIrritantHealth hazardEnvironmentalH315, H317, H319, H335, H341, H351, H360, H361, H362, H400, H410from source