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SHEET /m/lidocaine · PubChem CID 3676 · CAS 137-58-6 · REV 2026.07

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Lidocaine

from source

C14H22N2O · 234.34 g/mol

xylocaine · Duncaine · Esracaine · Gravocain

What is Lidocaine?

The local anaesthetic behind a numbed tooth, sold as Xylocaine, and the active ingredient in over-the-counter numbing creams and patches. from source

Chemical familyAromaticsAmides
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCCN(CC)CC(=O)NC1=C(C=CC=C1C)C

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
317 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

317 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values
  • 292 mg/kgLD50 · oral · mouse
  • 19.5 mg/kgLD50 · iv · mouse
  • 105 mg/kgLD50 · other · mouse
DangerIrritantHealth hazardH302, H317, H362, H370, H372from source

Sources & methodology

PubChem CID
3676
Wikidata
Q216935
Structure
PubChem → RDKit
LD50
PubChem
Data refreshed

How MoleculeFinder sources and labels its data