Ketoconazole
Also called Nizoral, Nizoral A-D, Ketozole and Extina.
An antifungal, familiar over the counter as the anti-dandruff shampoo Nizoral. Ketoconazole (C26H28Cl2N4O4, 531 g/mol) is an antifungal sold over the counter.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Sold over the counter, without a prescription.
Sources and notes
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A C=O bonded to a nitrogen, the same link that joins amino acids in a protein. It is sturdy, and its nitrogen is not a base the way an amine's is.
From: standard chemistry.
One carbon bonded to two oxygens, each joined in turn to another carbon. It is the kind of link that joins sugars together: it stands up to bases, and acid splits it.
From: standard chemistry.
An oxygen bridging two carbons, written C-O-C. It accepts hydrogen bonds but has no hydrogen to give, and it is slow to react.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C26H28Cl2N4O4
- Molecular weight
- 531.4 g/mol
- XLogP3octanol/water, log units
- 4.3
- Polar surface areatopological
- 69.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Rotatable bonds
- 7
- Complexity
- 735
Reported Licence
The US Food and Drug Administration licenses Ketoconazole for human use (NDA 020310, authorized October 10, 1997), as Nizoral Anti-Dandruff. Drugs@FDA
Groups it belongs to
- Category
- OTC medicine
- Family
- Antifungals
- Chemical groups
- Aromatics, Amides, Ethers, Halogenated
CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)ClPubChem CID 3823 · Wikidata Q407883 · InChIKey XMAYWYJOQHXEEK-UHFFFAOYSA-N · Data refreshed
Questions
- What is Ketoconazole?
- An antifungal, familiar over the counter as the anti-dandruff shampoo Nizoral. Ketoconazole (C26H28Cl2N4O4, 531 g/mol) is an antifungal sold over the counter.
- What kind of molecule is Ketoconazole?
- Ketoconazole has the formula C26H28Cl2N4O4 and a molecular weight of 531.4 g/mol. MoleculeFinder files it under antifungals, in the OTC medicine group. from sourcefrom sourcefrom sourcefrom source
- What else is Ketoconazole called?
- Ketoconazole is also called Nizoral A-D, Ketozole, Nizoral and Extina. from source
- Who licenses Ketoconazole as a medicine?
- The US Food and Drug Administration licenses Ketoconazole for human use (NDA 020310, authorized October 10, 1997), as Nizoral Anti-Dandruff. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09