moleculefinder

Guanfacine

C9H9Cl2N3O246.09 g/mol Calculated

Also called Intuniv and Tenex.

An alpha-2 agonist used for ADHD and high blood pressure, sold as Intuniv. Guanfacine (C9H9Cl2N3O, 246 g/mol) is an alpha-2 agonist dispensed on prescription.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Guanfacine on the product labels we hold.

Medicines

IntunivAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A carbon bonded to three nitrogens, one of them by a double bond, the same group the amino acid arginine carries. Its N-H groups form hydrogen bonds readily.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Properties and sources

Calculated by PubChem

Molecular formula
C9H9Cl2N3O
Molecular weight
246.09 g/mol
XLogP3octanol/water, log units
2
Polar surface areatopological
81.5 Ų
H-bond donors
2
H-bond acceptors
1
Rotatable bonds
2
Complexity
256

Reported Hazard label (GHS), ECHA via PubChem

Danger Toxic pictogram (GHS06), Health hazard pictogram (GHS08) and Environmental pictogram (GHS09); hazard statements H301, H361, H373, H411

Reported Licence

The US Food and Drug Administration licenses Guanfacine for human use (NDA 022037, authorized September 2, 2009). Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Alpha-2 agonists
Chemical groups
Amines, Aromatics, Halogenated
Elements
Chlorine, Nitrogen
Hazard classes
Acutely toxic, Health hazard, Environmental hazard, GHS Danger
SMILESC1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl

PubChem CID 3519 · Wikidata Q5613599 · InChIKey INJOMKTZOLKMBF-UHFFFAOYSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Guanfacine?
An alpha-2 agonist used for ADHD and high blood pressure, sold as Intuniv. Guanfacine (C9H9Cl2N3O, 246 g/mol) is an alpha-2 agonist dispensed on prescription.
How toxic is Guanfacine?
Its GHS hazard label carries the signal word Danger and the hazard pictograms Toxic, Health hazard and Environmental. from source
What kind of molecule is Guanfacine?
Guanfacine has the formula C9H9Cl2N3O and a molecular weight of 246.09 g/mol. MoleculeFinder files it under alpha-2 agonists, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
What else is Guanfacine called?
Guanfacine is also called Tenex and Intuniv. from source
Who licenses Guanfacine as a medicine?
The US Food and Drug Administration licenses Guanfacine for human use (NDA 022037, authorized September 2, 2009). from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09