SHEET /m/fluorouracil · PubChem CID 3385 · CAS 51-21-8 · REV 2026.07
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Fluorouracil
from sourceC4H3FN2O2 · 130.08 g/mol
Efudex · Tolak · Timazin · Fluoroplex
What is Fluorouracil?
A cancer medicine known as 5-FU, used for bowel and other cancers and as a cream for skin lesions. It is uracil with one fluorine atom swapped in. from source
CategoryPrescription medicine
Chemical familyHalogenated
Fig. 1 · 2D structure RDKit
SMILES
C1=C(C(=O)NC(=O)N1)FWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 115 mg/kg · moderately toxic
- Species
- mouse
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
115 mg/kg · moderately toxic · LD50 mouse oral from source
3 more reported values
- 30 mg/kgLD50 · oral · dog
- 81 mg/kgLD50 · iv · mouse
- 169 mg/kgLD50 · other · mouse
DangerToxicIrritantHealth hazardH301, H312, H315, H319, H335, H340, H341, H360, H372, H412from source
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Where Fluorouracil leads
Relatedcomputed