Ezetimibe
Also called Zetia, Ezedoc and Ezetrol.
A cholesterol medicine sold as Zetia. Unlike a statin it blocks cholesterol absorption in the gut rather than its manufacture.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourcePubChem / Wikidata
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Ezetimibe on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A C=O bonded to a nitrogen, the same link that joins amino acids in a protein. It is sturdy, and its nitrogen is not a base the way an amine's is.
From: standard chemistry.
An O-H fixed directly to a benzene ring. The ring makes that hydrogen easier to give up than an ordinary alcohol's, which is why many phenols act as antioxidants.
From: standard chemistry.
An O-H on a carbon that is not part of an aromatic ring, the group that makes a molecule an alcohol. It both gives and accepts hydrogen bonds, which helps the molecule mix with water.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C24H21F2NO3
- Molecular weight
- 409.4 g/mol
- XLogP3octanol/water, log units
- 4
- Polar surface areatopological
- 60.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 6
- Complexity
- 567
Reported Hazard label (GHS), ECHA via PubChem
Warning Environmental pictogram (GHS09); hazard statements H410
Reported Licence
The US Food and Drug Administration licenses Ezetimibe for human use (NDA 021445, authorized October 25, 2002), as Zetia. Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Cholesterol medicines
- Chemical groups
- Alcohols, Aromatics, Amides, Phenols, Halogenated
- Hazard classes
- Environmental hazard, GHS Warning
C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)OPubChem CID 150311 · Wikidata Q417997 · InChIKey OLNTVTPDXPETLC-XPWALMASSA-N · Data refreshed
Questions
- What is Ezetimibe?
- A cholesterol medicine sold as Zetia. Unlike a statin it blocks cholesterol absorption in the gut rather than its manufacture.
- How toxic is Ezetimibe?
- Its GHS hazard label carries the signal word Warning and the hazard pictogram Environmental. from source
- What kind of molecule is Ezetimibe?
- Ezetimibe has the formula C24H21F2NO3 and a molecular weight of 409.4 g/mol. MoleculeFinder files it under cholesterol medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- Who licenses Ezetimibe as a medicine?
- The US Food and Drug Administration licenses Ezetimibe for human use (NDA 021445, authorized October 25, 2002), as Zetia. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09