moleculefinder

Doxycycline

C22H24N2O8444.4 g/mol Calculated

Also called Doxiciclina, Doxytetracycline, Monodox and Vibra-tabs.

A tetracycline antibiotic used for chest and skin infections, acne, Lyme disease and as a malaria preventive.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourcePubChem / Wikidata
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Doxycycline on the product labels we hold.

Medicines

MonodoxAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A C=O bonded to a nitrogen, the same link that joins amino acids in a protein. It is sturdy, and its nitrogen is not a base the way an amine's is.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Compare a related molecule

Doxycycline

Azithromycin

Doxycycline and azithromycin both block bacterial protein making, but azithromycin is far larger and lingers in tissue, which is why its courses are short.

Doxycycline vs Azithromycin, side by side
Sources and notes
  • The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
  • The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.

Properties and sources

Calculated by PubChem

Molecular formula
C22H24N2O8
Molecular weight
444.4 g/mol
XLogP3octanol/water, log units
−0.7
Polar surface areatopological
182 Ų
H-bond donors
6
H-bond acceptors
9
Rotatable bonds
2
Complexity
956

Reported Licence

The US Food and Drug Administration licenses Doxycycline for human use (NDA 050641, authorized December 29, 1989), as Monodox. Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Antibiotics
Chemical groups
Alcohols, Aromatics, Ketones, Amides, Phenols
Elements
Nitrogen
SMILESC[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]…94 characters

PubChem CID 54671203 · Wikidata Q422442 · InChIKey SGKRLCUYIXIAHR-AKNGSSGZSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Doxycycline?
A tetracycline antibiotic used for chest and skin infections, acne, Lyme disease and as a malaria preventive.
What kind of molecule is Doxycycline?
Doxycycline has the formula C22H24N2O8 and a molecular weight of 444.4 g/mol. MoleculeFinder files it under antibiotics, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
Who licenses Doxycycline as a medicine?
The US Food and Drug Administration licenses Doxycycline for human use (NDA 050641, authorized December 29, 1989), as Monodox. from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09

Keep exploring

Sources and notes
  • Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
  • The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
  • The drawingscomputedPubChem structures, drawn by RDKit