Domperidone
Also called Domilium, Evoxin and Motilium.
An anti-nausea medicine that also speeds stomach emptying. It is widely used outside the United States, which has never approved it.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourcePubChem / Wikidata
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf.
Sources and notes
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A nitrogen bonded to three carbons, with no hydrogen of its own. Its spare pair of electrons can still pick up a hydrogen ion, so a tertiary amine is a base.
From: standard chemistry.
Fluorine, chlorine, bromine or iodine bonded to carbon. Each pulls electrons toward itself, and each is larger than the hydrogen the carbon would otherwise carry.
From: standard chemistry.
Rings joined where they share atoms, or a single ring standing alone. Atoms in a ring are held in place, so this part keeps its shape while chains around it can bend.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C22H24ClN5O2
- Molecular weight
- 425.9 g/mol
- XLogP3octanol/water, log units
- 3.9
- Polar surface areatopological
- 67.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Rotatable bonds
- 5
- Complexity
- 655
Reported Hazard label (GHS), ECHA via PubChem
Warning Health hazard pictogram (GHS08); hazard statements H361
Reported Licence
The Medicines and Healthcare products Regulatory Agency licenses Domperidone for human use, as Motilium. MHRA Products
Groups it belongs to
- Category
- Prescription medicine
- Family
- Anti-nausea medicines
- Chemical groups
- Aromatics, Halogenated
- Hazard classes
- Health hazard, GHS Warning
C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=OPubChem CID 3151 · Wikidata Q424238 · InChIKey FGXWKSZFVQUSTL-UHFFFAOYSA-N · Data refreshed
Questions
- What is Domperidone?
- An anti-nausea medicine that also speeds stomach emptying. It is widely used outside the United States, which has never approved it.
- How toxic is Domperidone?
- Its GHS hazard label carries the signal word Warning and the hazard pictogram Health hazard. from source
- What kind of molecule is Domperidone?
- Domperidone has the formula C22H24ClN5O2 and a molecular weight of 425.9 g/mol. MoleculeFinder files it under anti-nausea medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- Who licenses Domperidone as a medicine?
- The Medicines and Healthcare products Regulatory Agency licenses Domperidone for human use, as Motilium. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceMHRA ProductsRead 2026-10-21. Contains public sector information licensed under the Open Government Licence v3.0.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
Sources and notes
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit