SHEET /m/disulfiram · PubChem CID 3117 · CAS 97-77-8 · REV 2026.07
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Disulfiram
from sourceC10H20N2S4 · 296.5 g/mol
Antabuse · Abstinyl · Alcophobin · Antabus
What is Disulfiram?
Sold as Antabuse, used in alcohol dependence because drinking on it causes flushing and nausea. Its effect was noticed in rubber workers who handled it. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
CCN(CC)C(=S)SSC(=S)N(CC)CCWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 500 mg/kg · low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
500 mg/kg · low toxicity · LD50 rat oral from source
5 more reported values
- 1,980 mg/kgLD50 · oral · mouse
- 2,050 mg/kgLD50 · oral · rabbit
- 8,600 mg/kgLD50 · oral · rat
- 75 mg/kgLD50 · other · mouse
- 2,000 mg/kgLD50 · dermal · rabbit
DangerIrritantHealth hazardEnvironmentalH302, H303, H317, H319, H320, H332, H341, H361, H370, H372, H373, H400, H410from source