Digoxin
Also called Lanoxicaps, Lanoxin, Vanoxin and Lanoxin Pediatric.
A heart medicine extracted from the foxglove, used for atrial fibrillation and heart failure. William Withering wrote it up in 1785.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
Where you encounter it
Dispensed on prescription, not sold on a shelf. Digoxin on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
An ester closed into a ring: the C=O carbon and the oxygen beside it are both ring atoms. Like any ester, it can be split by water, which opens the ring.
From: standard chemistry.
An O-H on a carbon that is not part of an aromatic ring, the group that makes a molecule an alcohol. It both gives and accepts hydrogen bonds, which helps the molecule mix with water.
From: standard chemistry.
One carbon bonded to two oxygens, each joined in turn to another carbon. It is the kind of link that joins sugars together: it stands up to bases, and acid splits it.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C41H64O14
- Molecular weight
- 780.9 g/mol
- XLogP3octanol/water, log units
- 1.3
- Polar surface areatopological
- 203 Ų
- H-bond donors
- 6
- H-bond acceptors
- 14
- Rotatable bonds
- 7
- Complexity
- 1450
Measured LD50, HSDB via PubChem
17.78 mg/kg pure digoxin, mouse, oral
An LD50 is an animal study measurement, not a dose for a person.
Reported Hazard label (GHS), ECHA, HSDB via PubChem
Danger Toxic pictogram (GHS06), Irritant pictogram (GHS07), Health hazard pictogram (GHS08) and Environmental pictogram (GHS09); hazard statements H300, H319, H330, H331, H372, H400
Reported Licence
The US Food and Drug Administration licenses Digoxin for human use (NDA 020405, authorized September 30, 1997). Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Glycosides
- Hazard classes
- Acutely toxic, Irritant, Health hazard, Environmental hazard, GHS Danger
C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C…191 charactersPubChem CID 2724385 · Wikidata Q422222 · InChIKey LTMHDMANZUZIPE-PUGKRICDSA-N · Data refreshed
Questions
- What is Digoxin?
- A heart medicine extracted from the foxglove, used for atrial fibrillation and heart failure. William Withering wrote it up in 1785.
- How toxic is Digoxin?
- The reported LD50 of Digoxin is 17.78 mg/kg (mouse, oral). An LD50 is an animal study measurement, not a dose for a person. Its GHS hazard label carries the signal word Danger and the hazard pictograms Toxic, Irritant, Health hazard and Environmental. from sourcefrom source
- What kind of molecule is Digoxin?
- Digoxin has the formula C41H64O14 and a molecular weight of 780.9 g/mol. MoleculeFinder files it under glycosides, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- What else is Digoxin called?
- Digoxin is also called Lanoxicaps, Lanoxin, Vanoxin and Lanoxin Pediatric. from source
- Who licenses Digoxin as a medicine?
- The US Food and Drug Administration licenses Digoxin for human use (NDA 020405, authorized September 30, 1997). from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- LD50from sourceHSDB via PubChemOther values the sources report: mouse, another route, 3.964 mg/kg; rat, intravenous, 25 mg/kg; rat, another route, 30 mg/kg. The page shows the one LD50 the site uses everywhere.
- Hazard labelfrom sourceECHA, HSDB via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09