SHEET /m/colchicine · PubChem CID 6167 · CAS 64-86-8 · REV 2026.07
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Colchicine
from sourceC22H25NO6 · 399.4 g/mol
Colchineos · Colchisol · Colcrys · Mitigare
What is Colchicine?
A plant alkaloid from the autumn crocus, used for gout and pericarditis. It has been in the medicine chest since ancient Egypt. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OCWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 5.886 mg/kg · highly toxic
- Species
- mouse
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
5.886 mg/kg · highly toxic · LD50 mouse oral from source
3 more reported values
- 0.25 mg/kgLD50 · iv · cat
- 2 mg/kgLD50 · other · mouse
- 4.13 mg/kgLD50 · iv · mouse
DangerCorrosiveToxicHealth hazardH300, H310, H318, H330, H340from source