Clozapine

from source

C18H19ClN4 · 326.8 g/mol

Clorazil · Fazaclo · Fazaclo ODT · Leponex

What is Clozapine?

An atypical antipsychotic reserved for schizophrenia that has not responded to anything else, because it demands regular blood monitoring. from source

CategoryPrescription medicine

Chemical familyAmines Aromatics Halogenated

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESCN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50: 251 mg/kg · moderately toxic
Species: rat
Route: oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

251 mg/kg · moderately toxic · LD50 rat oral from source

3 more reported values

41.6 mg/kgLD50 · iv · rat
210 mg/kgLD50 · other · rat
240 mg/kgLD50 · other · rat

DangerToxicHealth hazardH301, H341, H351, H361from source

Keep roaming

Where Clozapine leads

Sources & methodology

PubChem CID: 135398737
Wikidata: Q221361
Structure: PubChem → RDKit
LD50: PubChem
Similar molecules: MoleculeFinder fingerprint similarity
Data refreshed: September 13, 2026

How MoleculeFinder sources and labels its data