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SHEET /m/cinnamaldehyde · PubChem CID 637511 · CAS 104-55-2 · REV 2026.07

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Cinnamaldehyde

from source

C9H8O · 132.16 g/mol

cinnamic aldehyde · trans-Cinnamic aldehyde · Benzylideneacetaldehyde · Cinnamyl aldehyde

What is Cinnamaldehyde?

The molecule that is cinnamon. It is most of the essential oil of cassia bark and the reason cinnamon feels warm as well as smelling sweet. from source

Chemical familyAromaticsAldehydes
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESC1=CC=C(C=C1)/C=C/C=O

The dose makes the poison inferred

A reported rat oral LD50 for Cinnamaldehyde is 3,400 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

238.0 g
a median lethal dose scaled to 154 lb (238,000 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Toxicity & hazards

Toxicity · LD50

3,400 mg/kg · very low toxicity · LD50 rat oral from source

The dose lens above scales this to a body weight.

3 more reported values
  • 200 mg/kgLD50 · oral · mouse
  • 75 mg/kgLD50 · iv · mouse
  • 200 mg/kgLD50 · other · mouse
WarningIrritantH312, H315, H317, H319, H335, H401, H412from source

Keep roaming

Where Cinnamaldehyde leads

Sources & methodology

PubChem CID
637511
Wikidata
Q204036
Structure
PubChem → RDKit
LD50
PubChem
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