SHEET /m/ciclosporin · PubChem CID 5284373 · CAS 59865-13-3 · REV 2026.07
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Ciclosporin
from sourceC62H111N11O12 · 1202.6 g/mol
cyclosporine A · CsA · CyA · cyclosporin A
What is Ciclosporin?
An immunosuppressant sold as Neoral and Sandimmune that made organ transplants routine in the 1980s. It was found in a fungus from a Norwegian soil sample. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N(…221 charactersWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 1,489 mg/kg · low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
1,489 mg/kg · low toxicity · LD50 rat oral from source
3 more reported values
- 24 mg/kgLD50 · iv · rat
- 147 mg/kgLD50 · other · rat
- 286 mg/kgLD50 · other · rat
DangerIrritantHealth hazardH302, H350, H360, H362, H370, H372from source