Buspirone
Also called Ansial and Bespar.
An anti-anxiety medicine sold as Buspar. It is not a benzodiazepine and is not sedating, which is why it is chosen for long-term anxiety.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourcePubChem / Wikidata
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf.
Sources and notes
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A nitrogen between two C=O groups. Both pull on the nitrogen, so a hydrogen on it comes off far more easily than one on an ordinary amide.
From: standard chemistry.
A nitrogen bonded to three carbons, with no hydrogen of its own. Its spare pair of electrons can still pick up a hydrogen ion, so a tertiary amine is a base.
From: standard chemistry.
Rings joined where they share atoms, or a single ring standing alone. Atoms in a ring are held in place, so this part keeps its shape while chains around it can bend.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C21H31N5O2
- Molecular weight
- 385.5 g/mol
- XLogP3octanol/water, log units
- 2.6
- Polar surface areatopological
- 69.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Rotatable bonds
- 6
- Complexity
- 529
Reported Hazard label (GHS), ECHA via PubChem
Danger Toxic pictogram (GHS06); hazard statements H301
Reported Licence
The US Food and Drug Administration licenses Buspirone for human use (ANDA 074253, authorized March 28, 2001). Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Anti-anxiety medicines
- Chemical groups
- Amides
- Elements
- Nitrogen
- Hazard classes
- Acutely toxic, GHS Danger
C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4PubChem CID 2477 · Wikidata Q412194 · InChIKey QWCRAEMEVRGPNT-UHFFFAOYSA-N · Data refreshed
Questions
- What is Buspirone?
- An anti-anxiety medicine sold as Buspar. It is not a benzodiazepine and is not sedating, which is why it is chosen for long-term anxiety.
- How toxic is Buspirone?
- Its GHS hazard label carries the signal word Danger and the hazard pictogram Toxic. from source
- What kind of molecule is Buspirone?
- Buspirone has the formula C21H31N5O2 and a molecular weight of 385.5 g/mol. MoleculeFinder files it under anti-anxiety medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- Who licenses Buspirone as a medicine?
- The US Food and Drug Administration licenses Buspirone for human use (ANDA 074253, authorized March 28, 2001). from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09