moleculefinder

Benzonatate

C30H53NO11603.7 g/mol Calculated

Also called Tessalon and benzononatine.

A cough medicine sold as Tessalon that numbs the stretch receptors in the airway. It is chemically related to local anaesthetics.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit

Where you encounter it

Dispensed on prescription, not sold on a shelf.

Sources and notes
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A C=O joined through an oxygen to another carbon, the link an acid and an alcohol make when they combine. Water can split it back into the two.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Properties and sources

Calculated by PubChem

Molecular formula
C30H53NO11
Molecular weight
603.7 g/mol
XLogP3octanol/water, log units
2.4
Polar surface areatopological
121 Ų
H-bond donors
1
H-bond acceptors
12
Rotatable bonds
33
Complexity
565

Reported Hazard label (GHS), ECHA via PubChem

Warning Irritant pictogram (GHS07); hazard statements H302, H315, H319, H335, H412

Reported Licence

The US Food and Drug Administration licenses Benzonatate for human use (NDA 011210, authorized February 10, 1958). Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Airway medicines
Chemical groups
Amines, Aromatics, Esters, Ethers
Elements
Nitrogen
Hazard classes
Irritant, GHS Warning
SMILESCCCCNC1=CC=C(C=C1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC

PubChem CID 7699 · Wikidata Q2070778 · InChIKey MAFMQEKGGFWBAB-UHFFFAOYSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Benzonatate?
A cough medicine sold as Tessalon that numbs the stretch receptors in the airway. It is chemically related to local anaesthetics.
How toxic is Benzonatate?
Its GHS hazard label carries the signal word Warning and the hazard pictogram Irritant. from source
What kind of molecule is Benzonatate?
Benzonatate has the formula C30H53NO11 and a molecular weight of 603.7 g/mol. MoleculeFinder files it under airway medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
What else is Benzonatate called?
Benzonatate is also called benzononatine. from source
Who licenses Benzonatate as a medicine?
The US Food and Drug Administration licenses Benzonatate for human use (NDA 011210, authorized February 10, 1958). from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09