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SHEET /m/acetylcysteine · PubChem CID 12035 · CAS 616-91-1 · REV 2026.07

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Acetylcysteine

from source

C5H9NO3S · 163.2 g/mol

N-acetyl-L-cysteine · NAC · mercapturic acid · Acetadote

What is Acetylcysteine?

A modified form of the amino acid cysteine, sold as a mucus thinner and used in hospitals as the antidote for paracetamol overdose. from source

CategoryOTC medicine
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCC(=O)N[C@@H](CS)C(=O)O

Where you'll find it

Sold over the counter, without a prescription. See the rest of the otc medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
3,000 mg/kg · very low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

3,000 mg/kg · very low toxicity · LD50 rat oral from source

4 more reported values
  • 1,000 mg/kgLD50 · oral · dog
  • 3,000 mg/kgLD50 · oral · mouse
  • 6,000 mg/kgLD50 · oral · rat
  • 700 mg/kgLD50 · other · dog
WarningIrritantH319from source

Keep roaming

Where Acetylcysteine leads

Sources & methodology

PubChem CID
12035
Wikidata
Q375613
Structure
PubChem → RDKit
LD50
PubChem
Similar molecules
MoleculeFinder fingerprint similarity
Data refreshed

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